List of publications

Overgaard, J. and MacMillan, H.A. (2017) The integrative physiology of insect chill tolerance. Annual Reviews in Physiology 79:187-208

Jensen, D.L., Overgaard, J., Wang, T., Gesser, H. and Malte, H. (2017). Temperature effects on aerobic scope and cardiac performance of European perch (Perca fluviatilis). Journal of Thermal Biology 68, 162-169.

O’Sullivan, J., MacMillan, H.A. and Overgaard J. (2017) Heat stress is associated with disruption of ion balance in the migratory locust, Locusta migratoria. Journal of Thermal Biology 68, 177-185.

Jørgensen, L.B., Overgaard, J. and MacMillan, H.A. (20167) Paralysis and heart failure precede ion balance disruption in heat-stressed European green crabs. Journal of Thermal Biology 68, 186-194.

Jørgensen, L.B. MacMillan, H.A. and Overgaard, J. (2017). Cold mortality is not caused by oxygen limitation or loss of ion homeostasis in the tropical freshwater shrimp Macrobrachium rosenbergii. Cryobiology 76, 146-149

Andersen, M.K., Jensen, S.O. and Overgaard, J. (2017) Physiological correlates of chill susceptibility in Lepidoptera. Journal of Insect Physiology 98, 317-326

Messamah, B., Malte, H., Loeschcke, V., Kellermann, V. and Overgaard, J. (2017) Metabolic cold adaptation contributes little to the interspecific variation in metabolic rates of 65 species of Drosophilidae. Journal of Insect Physiology 98, 309-316

Andersen, M.K., Folkersen, R., MacMillan, H.A., Overgaard, J. (2017) Cold acclimation improves chill tolerance in the migratory locust through preservation of ion balance and membrane potential. Journal of Experimental Biology 220, 487-496

Sørensen, J.G., Kristensen, T.N. and Overgaard, J. (2016) Evolutionary and ecological patterns of thermal plasticity in Drosophila: Is it important for keeping up with climate change? Current Opinions in Insect Science 17, 98-104

Olsson, T., MacMillan, H.A., Nyberg, N., Stærk, D., Malmendal, A. and Overgaard, J. (2016) Hemolymph metabolites and osmolality are tightly linked to cold tolerance of Drosophila species: a comparative study. Journal of Experimental Biology 219, 2504-2513

MacMillan, H., Schou, M.F., Kristensen, T.N. and Overgaard, J. (2016) Preservation of potassium balance is strongly associated with insect cold tolerance in the field: a seasonal study of Drosophila subobscura. Biology Letters. 12: 20160123. http://dx.doi.org/10.1098/rsbl.2016.0123

Dohn, N.B., Fago, A., Overgaard, J., Madsen, P.T. and Malte, H. (2016). Students’ motivation toward laboratory work in physiology teaching. Advances in Physiological Education 40: 313-318.

Rohde, P.D., Krag, K., Loeschcke, V., Overgaard, J., Sørensen, P. and Kristensen, T.N. (2016). A quantitative genomic approach for analysis of fitness and stress related traits in a Drosophila model population. International Journal of Genomics. 2016, Article ID 2157494, http://dx.doi.org/10.1155/2016/2157494

Findsen, A., Overgaard, J., and Pedersen. (2016) T.H. Reduced L-type Ca2+ current and compromised excitability induce loss of skeletal muscle function during acute cooling in locust. Journal of Experimental Biology. 219:2340-2348

Vanthournout, B., Greve, M., Madsen, A., Bechsgaard, J., Overgaard, J., Bilde, T. (2016). Benefits of group living include increased feeding efficiency and lower mass loss during desiccation in the social and inbreeding spider Stegodyphus dumicola. Frontiers in Physiology doi: 10.3389/fphys.2016.00018

Verberk, W.C.E.P., Overgaard, J., Ern, R., Bayley, M., Wang, T., Boardman, L., and Terblanche, J.S. (2016) Does oxygen limit thermal tolerance in arthropods? A critical review of current evidence. Comparative Biochemistry and Physiology A. 192: 64–78

MacMillan, H.A., Andersen, J.L., Davies, S.A. and Overgaard, J. (2015) The capacity to maintain ion and water homeostasis underlies interspecific variation in Drosophila cold tolerance. Scientific reports 5: 18607 | DOI: 10.1038/srep18607

Storz, J.F., Natarajan, C., Moriyama, H., Hoffmann, F.G., Wang, T., Fago, A., Malte, H., Overgaard, J. and Weber, R.E. (2015) Oxygenation properties and isoform diversity of snake hemoglobins. American Journal of Physiology. 309: R1178-R1191

MacMillan, H.A., Baatrup, E. and Overgaard, J. (2015) Concurrent effects of cold and hyperkalemia cause insect chilling injury. Proceedings of the Royal Society B 282, 1483.

Slotsbo, S., Sørensen, J., Holmstrup, M., Kostal, V., Kellermann, V. and Overgaard, J. (2015). Tropical to subpolar gradient in phospholipid composition suggests adaptive tuning of biological membrane function in drosophilids. Functional Ecology 30: 759-768.

Andersen, J.L., MacMillan, H.A. and Overgaard, J. (2015) Muscle membrane potential and insect chill coma. Journal of Experimental Biology 218, 2492-2495.

Andersen, J.L., MacMillan, H.A. and Overgaard, J. (2015) Temperate Drosophila preserve cardiac function at low temperature. Journal of Insect Physiology 77, 26-32

MacMillan, H.A., Andersen, J.L., Loeschcke, V. and Overgaard, J. (2015) Sodium distribution predicts the chill tolerance of Drosophila melanogaster raised in different thermal conditions. American Journal of Physiology 308: R823-R831.

Fisker, K.V., Bouvrais, H., Overgaard, J., Schöttner, K., Ipsen, J.H. and Holmstrup, M. (2015) Genetic differences in composition, fluorescence anisotropy, and bending rigidity of enchytraeid membranes originating from contrasting environments (Enchytraeus albidus). Comparative Physiology and Biochemistry A 185B: 389-400

Henriksen, P.S., Enok, S., Overgaard, J. and Wang, T. (2015) Food composition influences metabolism, heart rate and organ growth during digestion in Python regius. In press in Comparative Physiology and Biochemistry 183A. 36-44.

Kristensen, T., Overgaard, J., Lassen, J., Hoffmann, A. and Sgro, C. (2015) Low evolutionary potential for egg-to-adult viability in Drosophila melanogaster at high temperatures. Evolution 69: 803-14.

Andersen, J.L., Manenti, T., Sørensen, J.G., Loeschcke, V. and Overgaard, J. (2015) How to assess Drosophila cold tolerance: Chill coma temperature and lower lethal temperature are the best predictors of cold distribution limits. Functional Ecology 29: 55–65.

Fobian, D., Overgaard, J. and Wang, T. (2014) Oxygen transport is not compromised at high temperature in pythons. The Journal of Experimental Biology 217:3958-3961

Fisker, K.V., Holmstrup, M., Malte, H. and Overgaard, J. (2014) Effect of repeated freeze-thaw cycles on geographically different populations of the freeze tolerant worm Enchytraeus albidus (Oligochaeta). The Journal of Experimental Biology 217:3843-3852

van Heerwaarden, B., Lee, R. F. H., Overgaard, J. and Sgrò, C.M. (2014) No patterns in thermal plasticity along a latitudinal gradient in Drosophila simulans from eastern Australia. Journal of Evolutionary Biology 27:2541-53.

MacMillan, H.A., Findsen, A., Pedersen, T.H. and Overgaard, J. (2014). Cold-induced depolarization of insect muscle: Differing roles of extracellular K+ during acute and chronic chilling. The Journal of Experimental Biology 217: 2930-2938

Overgaard, J., Kearney, M.R. and Hoffmann, A.A. (2014) Sensitivity to thermal extremes in Australian Drosophila implies similar impacts of climate change on the distribution of widespread and tropical species. Global Change Biology 20: 1738–1750.

Findsen, A., Pedersen, T.H., Petersen, A.G., Nielsen O.B. and Overgaard, J. (2014) Why do insects enter and recover from chill coma? Low temperature and high extracellular potassium compromises muscle function in Locusta migratoria. Journal of Experimental Biology 217: 1297-1306

Overgaard, J., Sørensen, J.G., Com, E. and Colinet, H. (2014). The rapid cold hardening response of Drosophila melanogaster: Complex regulation across different levels of biological organization. Journal of Insect Physiology 62: 46-53.

Jensen, P., Overgaard, J., Loeschcke, V., Schou, M.F., Malte, H. and Kristensen, T.N. (2014) Inbreeding effects on standard metabolic rate investigated at cold, benign and hot temperatures in Drosophila melanogaster. Journal of Insect Physiology 62: 11-20.

Fisker, K.V., Overgaard, J., Sørensen, J. G., Slotsbo, S. and Holmstrup, M. (2014) Roles of carbohydrate reserves for local adaptation to low temperatures in the freeze-tolerant oligochaete Enchytraeus albidus. Journal of Comparative Physiology B 184: 167-177

Andersen, J.L., Findsen, A. Overgaard, J. (2013). Feeding impairs chill coma recovery in the migratory locust (Locusta migratoria). Journal of Insect Physiology 59: 1041–1048.

Kellermann, V., Overgaard, J., Loeschcke, V., Kristensen, T.N., Hoffmann, A.A. (2013) Trait Associations across Evolutionary Time within a Drosophila Phylogeny: Correlated Selection or Genetic Constraint? PLoS ONE 8(8): e72072. doi:10.1371/journal.pone.0072072

Malmendal, A., Sørensen, J.G., Overgaard, J., Holmstrup, M., Nielsen, NC, Loeschcke, V. (2013). Metabolomic analysis of the selection response of Drosophila melanogaster to different stresses, integrated with gene expression and phenotype. Naturwissenschaften 100: 417-27.

Findsen, A., Andersen, J.L., Calderon, S., and Overgaard, J. (2013). Rapid cold hardening improves recovery of ion homeostasis and chill coma recovery in the migratory locust Locusta migratoria. Journal of Experimental Biology 216: 1630-1637

Colinet, H., Overgaard, J., Com, E. and Sørensen, J.G. (2013). Proteomic profiling of thermal acclimation in Drosophila melanogaster. Insect Biochemistry and Molecular  Biology 43: 352-365.

Kristensen, T.N., Overgaard, J., Hoffmann, A.A., Nielsen, N-C. and Malmendal A. (2012) Inconsistent effects of developmental temperature acclimation on low temperature performance and metabolism in Drosophila melanogaster. Evolutionary Ecology Research 14, 821-837. 

Kellermann, V., Overgaard, J., Hoffmann, A.A., Fløjgaard, C., Svenning, J-C. and Loeschcke, V. (2012). Upper Thermal Limits of Drosophila are linked to Species Distributions and Strongly Constrained Phylogenetically. Proceedings of the National Academy of Sciences 109: 16228-33. 

Overgaard, J., Andersen, J.L., Findsen, A., Pedersen, P.B.M., Hansen, K., Ozolina, K. and Wang, T. (2012). Aerobic scope and cardiovascular oxygen transport is not compromised at high temperatures in the toad Rhinella marina. Journal of Experimental Biology 215: 3519-26. 

Kellermann, V., Loeschcke, V., Hoffmann, A.A. Kristensen, T.N., Fløjgaard, C., David, J., Svenning, J-C., and Overgaard, J. (2012). Phylogenetic constraints in key functional traits behind species' climate niches: patterns of desiccation and cold resistance across 96 Drosophila. Evolution. 66: 3377-3389. 

Overgaard J, Kristensen TN, Sørensen JG (2012) Validity of Thermal Ramping Assays Used to Assess Thermal Tolerance in Arthropods. PLoS ONE 7(3): e32758. doi:10.1371/journal.pone.0032758. 

Overgaard, J., Kristensen, T.N., and Hoffmann, A.A. (2011). Assessing population and environmental effects on thermal resistance in Drosophila melanogaster using ecologically relevant assays. Journal of Thermal Biology 36: 409-416 

Kristensen, T.N., Overgaard, J., Loeschcke, V. and Mayntz, D. (2011) Dietary protein content affects evolution for body size, body fat and viability in Drosophila melanogaster.  Biology Letters 7: 269-272. 

Holmstrup, M., Sørensen, J.G., Overgaard, J., Bayley, M., Bindesbøl, A-M., Slotsbo, S., Fisker, K., Maraldo, K., Waagner, D., Labouriauc, R. and Asmund, G. (2011). Body metal concentrations and glycogen reserves in earthworms (Dendrobaena octaedra) from contaminated and uncontaminated forest soil. Envronmental Pollution 159: 190-197.

Overgaard, J., Kristensen, T.N., and Hoffmann, A.A. (2011). Assessing population and environmental effects on thermal resistance in Drosophila melanogaster using ecologically relevant assays. Journal of Thermal Biology 36: 409–416.

Overgaard, J., Kristensen, T.N., Mitchell, K.A. and Hoffmann, A.A. (2011) Thermal tolerance in widespread and tropical Drosophila species: Does phenotypic plasticity increase with latitude? American Naturalist 178: S80–S96.

Jensen, K., Mayntz, D., Wang, T., Simpson, S.J., and Overgaard, J. (2010). Metabolic consequences of feeding and fasting on nutritionally different diets in the wolf spider Pardosa prativaga. Journal of Insect Physiology 56: 1095-1100.

Bayley, M., Overgaard, J., Høj, A.S., Malmendal, A., Nielsen, N.C., Holmstrup, M. and Wang, T. (2010). Metabolic changes during aestivation in the common earthworm Aporrectodea caliginosa. Physiological and Biochemical Zoology 83: 541-550.

Gesser, H. and Overgaard, J. Comparative aspects of hypoxia tolerance of the ectothermic vertebrate heart (2010). In Cardio-Respiratory Control in Vertebrates. Ed. Glass, M.L.and Wood, S., Springer-Verlag.

Sgrò, C.M., Overgaard, J., Kristensen, T.N., Mitchell, K., Cockerell, F. and Hoffmann, A.A. (2010). A comprehensive assessment of geographic variation in heat tolerance and hardening capacity in populations of Drosophila melanogaster from eastern Australia. Journal of Evolutionary Biology 23: 2484-2493.

Overgaard, J. Sørensen, J.G. and Loeschcke, V. (2010) Genetic Variability and Evolution of Cold Tolerance. In Low Temperature Biology of Insects. Ed. Denlinger, D. and Lee, R.E., Cambridge University Press.

Overgaard, J., Sørensen, J.G., Jensen, L.T., Loeschcke, V. and Kristensen, T.N. (2010) Field tests reveal genetic variation for performance at low temperatures in Drosophila melanogaster. Functional Ecology, 24: 186–195.

Overgaard, J, Tollarova, M, Hedlund, K, Petersen, S.O. and Holmstrup, M. (2009) Seasonal changes in lipid composition and glycogen storage associated with freeze-tolerance of the earthworm, Dendrobaena octaedra. Journal of Comparative Physiology B 179: 569-577.

Calderon, S., Holmstrup, M., Westh, P. and Overgaard, J. (2009) Dual roles of glucose in the freeze-tolerant earthworm Dendrobaena octaedra: cryoprotection and fuel for metabolism. Journal of Experimental Biology 212: 859-866.

Stecyk, J. A. W., Bock, C., Overgaard, J., Wang, T.,  Farrell, A. P., Pörtner, H-O. (2009) Correlation of cardiac performance with cellular energetic components in the oxygen-deprived turtle heart. American Journal of Physiology 297: R756-R768.

Overgaard, J., Sørensen, J.G. (2008). Rapid thermal adaptation during field temperature variations in Drosophila melanogaster. Cryobiology 56: 159-162

Overgaard, J., Tomčala, A., Sørensen, J.G., Holmstrup, M., Krogh, P.H. Šimek, P., Koštál, V. (2008). Effects of acclimation temperature on thermal tolerance and membrane phosholipid composition in the fruit fly Drosophila melanogaster. Journal of Insect Physiology 54: 619-629

Kristensen, T.N., Hoffmann, A.A., Overgaard, J., Sørensen, J.G., Hallas, R., Loeschcke, V. (2008). Costs and benefits of cold acclimation in field released Drosophila. Proceedings of the National Academy of Sciences 105: 216-221.

Petersen, C. R., Holmstrup, M., Malmendal, A., Bayley, M., Overgaard, J. (2008) Slow desiccation improves dehydration tolerance and accumulation of compatible osmolytes in earthworm cocoons (Dendrobaena octaedra). Journal of Experimental Biology 211: 1903-1910.

Overgaard, J., Holmstrup, M. (2008) A response: Cryoprotectants do not only have colligatively based functions. Cryoletters 29, 270.

Jensen, D., Overgaard, J., Sørensen, J.G. (2007) The influence of developmental stage on cold shock resistance and the ability to rapidly cold-harden in Drosophila melanogaster. Journal of Insect Physiology 53: 179–186.

Holmstrup, M., Overgaard, J., Bayley, M. (2007) Small Dendrobaenaearthworms survive freezing better than large worms. Cryobiology 54: 298–300.

Overgaard, J., Malmendal, A., Sørensen, J.G., Bundy, J., Loeschcke, V., Nielsen, N. and Holmstrup, M. (2007) Metabolomic profiling of rapid cold hardening and cold shock in Drosophila melanogaster. Journal of Insect Physiology 53: 1218-1232

Holmstrup, M., Overgaard, J. (2007) Freeze tolerance in Aporrectodea caliginosa and other earthworms from Finland. Cryobiology 55: 80-86

Bahrndorff, S., Petersen, S.O., Loeschcke, V., Overgaard, J. and Holmstrup, M. (2007) Differences in cold and drought tolerance of high arctic and subarctic populations of Megaphorura arctica (Collembola). Cryobiology 55: 315-323.

Overgaard, J., Slotsbo, S., Holmstrup, M. and Bayley, M. (2007) Determining factors for cryoprotectant accumulation in the freeze tolerant earthworm,Dendrobaena octaedra. Journal of Experimental Zoology 307A: 578-589.

Zaar, M., Overgaard, J., Gesser, H. and Wang, T. (2007) Contractile properties of the functionally divided python heart: Two sides of the same matter. Comparative Physiology and biochemistry A. 146: 163–173.

Overgaard, J., Gesser, H. and Wang, T. (2007) Cardiac performance and cardiovascular regulation during anoxia/hypoxia in freshwater turtles. Journal of Experimental Biology 210: 1687-1699.

Holmstrup, M., Overgaard, J., Bindesbøl, A., Pertoldi, C. and Bayley, M. (2007) Adaptations to overwintering in the earthworm Dendrobaena octaedra: Genetic differences in glucose mobilisation and freeze tolerance. Soil Biology and Biochemistry 39: 2640-2650.

Overgaard, J., Sørensen, J. G., Petersen, S.O., Loeschcke, V. and Holmstrup. M. (2006). Reorganisation of membrane lipids during fast and slow cold hardening in Drosophila melanogaster. Physiological Entomology. 31: 328-335.

Tomčala, A., Tollarová, M., Overgaard, J., Šimek, P., Koštál, V. (2006) Seasonal acquisition of chill-tolerance and restructuring of membrane glycerophosholipids in an overwintering insect: triggering by low temperature, desiccation and diapause progression. Journal of Experimental Biology. 209: 4102-4114.

Malmendal, A., Overgaard, J., Bundy, J.G., Sørensen, J.G., Nielsen, N., Loeschcke, V., Holmstrup, M. (2006) Metabolomic Profiling of Heat Stress: Hardening and Recovery of Homeostasis in Drosophila. American Journal of Physiology, Regulatory Integrative and Comparative Physiology. 291: R205 – R212.

Holmstrup, M., Overgaard, J., Sørensen, T.F., Drillet, G., Hansen, B.W., Ramløv, H. and Engell-Sørensen, K. (2006) Influence of storage conditions on viability of quiescent copepod eggs (Acartia tonsa Dana): Effects of temperature, salinity and anoxia. Aquaculture Research. 37, 625-631.

Nielsen, M. M., Overgaard, J., Sørensen, J. G., Holmstrup, M., Justesen, J. Loeschcke, V. (2005) Role of HSF activation during cold hardening and for high temperature knock-down resistance. Journal of Insect Physiology, 51(12), 1320-1329.

Overgaard, J., Wang, T., Nielsen, O. B. and Gesser, H. (2005) Extracellular determinants of cardiac contractility in the cold, anoxic turtle. Physiological and Biochemical Zoology, 78(6), 976-995.

Overgaard, J., Sørensen, J. G., Petersen, S. O., Loeschcke, V. and Holmstrup, M. (2005) Changes in membrane lipid composition following rapid cold hardening in Drosophila melanogaster. Journal of Insect Physiology, 51(11), 1173-1182.

Stecyk, J.A.W., Overgaard, J., Farrell, A.P. and Wang, T. (2004) α-Adrenergic regulation of systemic peripheral resistance and blood flow distribution in the turtle Trachemys scripta during anoxic submergence at 5°C and 21°C. Journal of Experimental Biology, 207, 269-283.

Overgaard, J., Stecyk, J.A.W., Gesser, H., Wang, T., Gamperl, A.K., and Farrell, A.P. (2004) Preconditioning stimuli do not benefit the myocardium of hypoxia-tolerant rainbow trout (Oncorhynchus mykiss). Journal of Comparative Physiology B. 174, 329-340.

Overgaard, J. and Gesser, H. (2004) Force development, energy state and ATP production of cardiac muscle from turtles and trout during normoxia and severe hypoxia. Journal of Experimental Biology, 207, 1915-1924.

Overgaard, J., Stecyk, J. A. W., Gesser, H., Wang, T. and Farrell, A. P. (2004) Effects of temperature and anoxia upon the performance of in situ perfused trout hearts. Journal of Experimental Biology, 207, 655-665.

Wang T., Zaar M., Arvedsen S., Vedel-Smith C., Overgaard J. (2003). Effects of temperature on the metabolic response to feeding in Python molurus. Comparative Biochemistry and Physiology. 133 A, 519-527.

Overgaard J., Andersen J.B. and Wang T. (2002). The effects of fasting duration on the metabolic response to feeding in Python: An evaluation of the energetic costs associated with gastrointestinal growth and upregulation. Physiological and Biochemical Zoology. 75(4). 360­-368.

Overgaard J. and Wang T. (2002). Increased blood oxygen affinity during digestion in the snake Python molurus. Journal of Experimental Biology. 205, 3327-3334.

Overgaard J., Stecyk J.A.W., Farrell A.P., and Wang T. (2002). Adrenergic control of the cardiovascular system in the turtle Trachemys scripta. Journal of Experimental Biology. 205, 3335-3345.

Wang T., Busk M and Overgaard J. (2001). The respiratory consequences of feeding in amphibians and reptiles. Comparative Biochemistry and Physiology. 128 A, 535-549.

Busk M., Overgaard J., Hicks J. W., Bennett A. F., and Wang T. (2000). Effects of feeding on arterial blood gases in the American alligator Alligator mississippiensis. Journal of Experimental Biology. 203, 3117-3124.

Overgaard J., Busk M., Hicks J. W., Jensen F. B. and Wang T. (1999). Respiratory consequences of feeding in the snake Python molurus. Comparative Biochemistry and Physiology. 124 A, 359-365.